感染有助于口咽癌症的高率

虽然头部和颈部癌症的总体发病率落在美国，但口咽（主要是，扁桃体和舌头）癌症的速度仍然停滞，似乎升高是某些人口，这些趋势可能是由于致癌人类乳头瘤病毒（HPV）感染。在2007年10月1日发表的审查，癌症的同伴审查的美国癌症协会杂志，发现了口咽癌症发病率的趋势，特别是45岁以下的男性，其中HPV感染可能是可能的原因。

Cancers of the head and neck, which include cancers of the larynx, nasal passages/nose, oral cavity, pharynx, and salivary glands, account for three percent of all newly diagnosed cancers in the U.S. Men are three times more likely to be diagnosed with these cancers than women. Of the estimated 45,000 new cases of head and neck cancers expected this year, approximately 10,000 are cancers of the pharynx (chiefly the oropharynx). Though the prognosis for these cancers is excellent when caught early, more than half of them are identified in advanced stages, when the prognosis is far worse, making prevention critical to saving lives.

在他们的评论中，Erich M. Sturgis，M.D.，M.P.H.和保罗·辛迪利亚尼，博士。of The University of Texas M. D. Anderson Cancer Center in Houston, conclude that the stagnate incidence rates of oropharyngeal cancers, particularly cancers of the tonsil and base of tongue, in the face of declines in tobacco use, the principal cause of head and neck cancers, are likely explained by rising prevalence of oropharyngeal exposure to an oncogenic virus. They say the literature points to exposure to HPV – especially strain 16 – as having the strongest association to oropharyngeal cancers. However, the authors suggest that a recently approved HPV vaccine may ultimately have a significant impact on the incidence of oropharyngeal tumors.

“虽然赞扬宫颈癌和发育不良预防政策的颈部癌症和发育不良政策，但担心疫苗的疫苗接种，我们担心限于女性的疫苗接种计划仅延迟预防HPV16 / 18相关的口咽癌症的潜在益处，通常发生在男人身上，“缔结作者。

作者“鼓励快速研究雄性中这些疫苗的疗效和安全性，如果成功，则是年轻成人和青少年雄性疫苗接种的推荐。”

资料来源：John Wiley＆Sons

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