艾滋病毒治疗用途在美国增加

Between 2000 and 2008, the proportion of HIV-infected patients in the U.S. receiving effective treatment known as highly active antiretroviral therapy (HAART) increased, and HIV-infected patients appeared to be less infectious and have healthier immune systems at death, according to a study led by researchers at the Johns Hopkins Bloomberg School of Public Health. The study was nested in the NA-ACCORD (North American AIDS Cohort Collaboration on Research and Design), which is the largest cohort of HIV-infected adults in North America. The findings are published in the September 4 edition of内科。

该研究包括超过45,000名艾滋病毒感染的参与者接受艾滋病毒的临床护理。根据国家的说法，研究人口与艾滋病毒的美国人口与美国人口相似。监控数据来自疾病预防与控制中心。在研究期间，研究人员发现，所列HAART的艾滋病毒感染者的比例增加了9个百分点至83％。在此期间，研究人员还观察到艾滋病毒的病毒载荷抑制的增加，无论治疗如何。抑制病毒载量降低了可能性传输艾滋病毒对他人。在那些携带HAART中，抑制病毒载量的比例从54％增加到81％。

“这是一个好消息艾滋病毒流行in the U.S., but there is room for improvement," said Keri N. Althoff, PhD, MPH, lead author of the study and assistant professor in the Bloomberg School's Department of Epidemiology. "We need to continue to focus on linking HIV-infected adults into care and effective treatment, not only for the individual's health, but to reduce the likelihood of transmission to others."

该分析还发现，在研究期间，从艾滋病毒中死亡的参与者中位CD4计数增加。在60个细胞/ mm3至209个细胞/ mm3的死亡时中位数增加。更高的CD4计数表明了更健康的免疫系统。计划额外研究调查死亡原因的趋势。

“我们的研究表明，Na-Accor的数据可用于监测艾滋病毒的成年人中的重要健康指标，这是评估实惠的护理法案的影响并衡量国家艾滋病毒战略目标的进展，”Althoff说。

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