心脏手术中的输血可能会感染
（健康日）在手术期间或之后进行红细胞（RBC）可能会增加主要感染的风险，例如肺炎和血液感染，如6月份的研究胸外科史册。
Keith A. Horvath, M.D., of the National Institutes of Health in Bethesda, Md., and colleagues conducted an observational study of 5,158 adults undergoing cardiac surgery at 10 medical centers in the United States and Canada to identify practices in medical management associated with risk for infections. The effects of blood and platelet transfusions on major infections within 60 ± 5 days following surgery were examined.
研究人员发现，接受心脏手术的患者分别在48％和31％中转发RBC和血小板。每个RBC输血与主要感染的粗暴风险的增加29％显着相关。最常见的术后感染是肺炎（3.6％）和血流感染（1.9％）。与感染风险增加相关的因素包括术后，手术持续时间和手术持续时间（移植或植入心室辅助装置）的RBC单位数，以及患者特征，包括合并条件如慢性阻塞性肺疾病心力衰竭，术前血清肌酐水平升高。血小板输血显着降低了术后感染的风险。
“这里报告的调查结果是Sobering：每单位红细胞transfused, the risks of infection increase 29 percent," Bruce D. Spiess, M.D., of the Virginia Commonwealth University Medical Center in Richmond, writes in an accompanying editorial. "Medicine is in need of a new and educated contemporary methodology for deciding when a transfusion should be indicated and useful."
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