IDSA:口服摄入可行的粪便微生物移植
![For patients with recurrent <i>Clostridium difficile</i> infection (rCDI), fecal microbiome transplantation via ingestion of fecal microbes is well-tolerated and arrests rCDI, according to a study presented at the annual meeting of the Infectious Diseases Society of America (IDWeek), held from Oct. 2 to 6 in San Francisco. IDSA:口服摄入可行的粪便微生物移植](https://scx1.b-cdn.net/csz/news/800a/2013/idsaoralinge.jpg)
(每日健康)——复发患者艰难梭状芽胞杆菌感染(rCDI)、粪便微生物通过摄入粪便微生物移植耐受和逮捕rCDI,据一项研究发表在美国传染病学会的年会(IDWeek),从10月2日至6日在旧金山举行。
托马斯•路易医学博士,from the University of Calgary in Canada, and colleagues conducted a study involving 27 patients with rCDI infection who could not tolerate a jejunal catheter and/or were unable to retain fecal enemas. Fecal微生物分离得到新鲜粪便通过相关的捐赠者和插入明胶胶囊,双overcapsulated。收件人摄取24到34刚组装胶囊在5到15分钟。
研究人员发现过程喷雾耐受良好且无胶囊后病人呕吐摄入。微生物数量和内容相似的捐赠粪便样本和胶囊沉积物。一个口腔手术后,所有逮捕了rCDI接受者。粪便微生物移植后,显著增加的数量拟杆菌,球菌样的梭状芽胞杆菌,leptum梭状芽胞杆菌,普氏菌,双歧杆菌,脱磷孤菌属;降低被认为在肠杆菌科和韦永氏球菌属。
“药片是一次性交易,似乎工作。他们更容易病人和耐受良好,”路易在一份声明中说。
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