脂肪,蛋白质影响后葡萄糖偏移在T1DM中
(健康日) - 使用型胰岛素治疗(IIT)的1型糖尿病的儿童(IIT),高脂肪(HF)和高蛋白质(HP)膳食增加葡萄糖偏移,并根据12月发表的一项研究,观察到添加剂效果。问题在于糖尿病护理。
Carmel E.M. Smart, R.D., Ph.D., from the John Hunter Children's Hospital in Newcastle, Australia, and colleagues examined the separate and combined effects of HP and HF meals on postprandial glycemia in 33 children, aged 8 to 17 years, using IIT. Participants were given four test breakfasts that had the same carbohydrate content but differed with respect to quantities of protein (low, 5 g or high, 40 g) and fat (low, 4 g or high, 35 g): low fat (LF)/low protein (LP), LF/HP, HF/LP, and HF/HP. For each meal, an individually standardized insulin dose was given. Five-hour continuous葡萄糖监测用于评估餐后葡萄糖。
研究人员发现,与LF / LP膳食后210分钟后,平均葡萄糖偏移从180分钟,与LF / LP膳食分别相比,210分钟(分别为0.02和0.01)。与所有其他膳食相比,HF / HP膳食后180至300分钟的葡萄糖偏移更高(P <0.04)。HP膳食后低血糖的风险降低(差距,0.16; P <0.001)。
“总之,这是第一项证明蛋白质和脂肪的研究饭菜作者写道,含有相同的碳水化合物量导致延长的儿童后期高血糖血症。
该项目得到了辉瑞澳大利亚儿科内分泌护理研究的补助金。
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