延迟pregnancy-heart,妈妈和儿子,健康风险研究显示

推迟怀孕可能会增加患心血管疾病的风险在这两个妇女和他们的孩子,男孩在疾病的风险更高,根据一项新的研究。来自加拿大阿尔伯塔大学的研究人员将他们的研究结果在今天美国生理协会(APS)心血管、肾和代谢疾病:对生理性别影响会议在诺克斯维尔,田纳西州。

先前的研究已经发现先进的母亲的年龄-35岁或以上在pregnancy-increases血管功能受损的风险和减少胎盘血流量。这些问题危害胎儿的增长和整体健康和可能导致心脏病孕妇的生命。人员分组一个鼠模型先进的母亲的年龄怀孕状态,包括“从未怀孕,”“产后”和“流产”。They found the pregnancy loss group had less widening of the blood vessels (vasodilation) compared to the groups that were never pregnant or had recently delivered. In some cases, less vasodilation may lead to decreased vascular health. In addition, the postpartum group had reduced vasodilation in the arteries of the intestines. "These data demonstrate mechanisms which may lead to worsened outcomes at an advanced maternal age, including early pregnancy termination, and later life cardiovascular dysfunction," the research team wrote.

研究人员还发现健康风险上的性别差异的年长的老鼠的后代。男性天生产后组受损的血管内膜和函数心脏危险因素与中断相关血液流动。雌性后代没有显示相同的危险因素。“鉴于上升趋势推迟怀孕,我们的研究结果有显著的人口和卫生保健的影响,进一步说明怀孕机会评估心血管健康,”研究人员写道。