肥胖可能会改变对Covid-19的免疫系统反应
根据在内分泌协会的杂志上发表的新手稿,肥胖症可能导致对Covid-19感染的过度免疫系统对Covid-19感染的反应,这使得难以消除病毒,内分泌学。
肥胖不仅导致问题心脏病和糖尿病,也影响了免疫系统很多方面。肥胖导致免疫系统某些部位的慢性低,低等级激活。当具有这种预先存在的病情的某人面临感染时,这可能导致免疫系统的超激活,但以不抗击感染的不利方式。
“Covid-19大流行使我们意识到肥胖的复杂互动传染性疾病以及我们对如何理解的差距慢性健康状况affect our immune responses to acute infection," said the study's corresponding author, Durga Singer, M.D., of the University of Michigan in Ann Arbor, Mich. "Recent evidence has highlighted how one part of the immune system, the macrophage, may be a culprit in driving severe COVID-19 disease. Our manuscript focuses on what is already known about the interaction of obesity, macrophages and other infections like influenza. These findings highlight the importance of understanding how obesity might interact with new drugs or vaccines that are developed for COVID-19."
在本综述中,作者描述了肥胖对免疫系统的影响。他们讨论了肥胖引起的不规则免疫反应,使器官损伤在严重的Covid-19感染中造成损害一个人对抗病毒的能力。
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