%PDF-1.7 % 14 0 obj << /Type /Page /Parent 1 0 R /LastModified (D:20220923045922-04'00') /Resources 2 0 R /MediaBox [0.000000 0.000000 595.276000 841.890000] /CropBox [0.000000 0.000000 595.276000 841.890000] /BleedBox [0.000000 0.000000 595.276000 841.890000] /TrimBox [0.000000 0.000000 595.276000 841.890000] /ArtBox [0.000000 0.000000 595.276000 841.890000] /Contents 15 0 R /Rotate 0 /Group << /Type /Group /S /Transparency /CS /DeviceRGB >> /Annots [ 6 0 R 7 0 R 8 0 R 9 0 R 10 0 R ] /PZ 1 >> endobj 15 0 obj <> stream x\]s۶}S̐Iۛfno IhHBH)ｻHSidJn((`?B|#.óo~` ~tOw_$q'3ȫgG\^<|/MYoF_{oSognÉGǨvlzq%i ((w/-׍XFȚpj^h=0헱 cy#؊Z7Pe#6%Xp ;ѬG,IC "BL18_rB&l?u?IY`27r˫WA5.}ĩ7K,g|FŻ2*sni:|2Ԛk8k*^7&rYsUk+pM1gv7疼F|Jq#"?8?a[pZ&\`eJfr1>вE{lF0b/%9H- ,[-o׼y'6z&ͥ*D"w,X`dfܬR"k`% =GbCX6U+8]G[KAf˃9+!"n|~i$۫77/^v~/;FQ99RGyed L8! aGR{<<8_ODD4q9$wiLR )X@D3K%I+ާ"G$h{}%'?G%ԑsEڃ+VO P)YRxr9~XcǑRnH{qkDwdgSKY` bCo~g@Q`$sHrO BDmkJȆ(y芕%J:R|98o9$s 5|=H,*ũ5ێ߆PcFBX=6㵒%4D'w{Z?2^W %?Ay(9:01,kncafwBsf%[tɇ(_ytA8=swWfX>b%Rk4 VUu%Ɵc N]yZ)X\>+Ə0:6s:`drSB[7@PC[c0VfNעLGDVL%_g.u[3F2 ƥWL>M|q{E-"C=T~S/3?LnyU"X%:^4s=N`DQ-k֏\Z/X 1"7h˶L'0:԰N舘3LlIu8QRr{c# #yhrYLcȃ˹4(h1iQUl ,4d#kb$d[[>6Wݹl[! hj ;5G.[uZ6HM$ \D7m!th2tҥPu={.xnn73bb/n; RmgP?) <8m^dO@L7Cese f,4v;key;4Jg`7ߒL %]6TLM-ӄᰕ42`КxS HH4 #\j_\reCj#)zf4G\i>s Q]9Ie-_&NpZf0>:x,8~|ؤ"u8nGqX&ojHGHsLHX틛::x4xJ95ÀZ|Mw\6uG?0&\{`υDJQҰLLA7rK4AoÜn2̥0[YScgX8ٰ,{:`V=k;}7Qo}1%y'܊Z\W\aZõk?w 7FFNo]3WK'ް{QĻ^>zع(A1&YL%I t(2w{S?Y &/U endstream endobj 16 0 obj << /Type /Page /Parent 1 0 R /LastModified (D:20220923045922-04'00') /Resources 2 0 R /MediaBox [0.000000 0.000000 595.276000 841.890000] /CropBox [0.000000 0.000000 595.276000 841.890000] /BleedBox [0.000000 0.000000 595.276000 841.890000] /TrimBox [0.000000 0.000000 595.276000 841.890000] /ArtBox [0.000000 0.000000 595.276000 841.890000] /Contents 17 0 R /Rotate 0 /Group << /Type /Group /S /Transparency /CS /DeviceRGB >> /Annots [ 11 0 R 13 0 R ] /PZ 1 >> endobj 17 0 obj <> stream xVMs0W챙 LnnttCId@8|Syվ%ܧؠ 'kI|ygLzC`ۄ 1=yIxhnX^'wCCU?[fwKp;#u)a9, l\KBxbtv=tn}_x%<70ó!DF3Q9iF OCE*G( D3$Ee fF3qZY޻ArE  ʑ".*\}`UD>=ԍRD́ QnQ`Ua Y%T/?Jd1PTOdƔADQԢH~!ߤβm+iwHZjKRg˼w[.e(@0.`9ͯ pM Sޜi#wd)D\)4tt#bFAʹ669#!Q&  (T5RYdTfQ""qZ{T}-> endobj 3 0 obj <> endobj 5 0 obj <> endobj 12 0 obj <> endobj 18 0 obj <> stream JFIFHHExifMM* z(1>?QQ Q HHPaint.NET v3.5.10z%u0`:oCC." }!1AQa"q2#BR$3br %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz w!1AQaq"2B #3Rbr $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ?(f 1T$`9Sw(B@;~(]Cd꾫Es:aݻd2\(2F][&]ۢϲ|W͵L@A A 8 (CĝCglZE/ |Ezє{ xQʒ@[ྊ\/I4R0?6.7`ŴwPu|3/Z@Ogi}cFdFKoj?~8|p_A<ĺOkGPK $wRmkmF;YVx&rLj#p ׭axf|s$Ӿc:Qwm]N)Cψ[eYba98xB+oTÚwcRþ$U[ ?qΙ{&jv6Xo$=ԗ&7zgAxIִ.$3,mwc{+%g[!U@&Fϻm/#hci'7n[%It.&/ֶ+Zl~:wi~D>$}o+}@.[/+B6mnt8bi{zc.~F{eUe86g3 VT&> BK VؘXzSMesoM_&ϔIÍK?+hڿnt_ K]H '̽yrWA=O+|"!gɤItXe>Xs hwwG Eouqa /ş_~~'x} ]_^]/ 蚼:<cu/ h&omEۯicǪ\[,k}_uS}㏆W]G^tmf`Ks ]=va&h9n忔>75NWQτ0of,E (˰8hBC_ Jq'W UQKz,N>+`S%}b5ISJ]+(&QVN>eoy7xG4[]]3K{i$I>g-(mbynLIC,"*3f?-%`lfPx涽X"H'h"ֈ(TfeU:܉,a,R*I4xcxalOhGр|ia$cg,{gAHEu->]F,{-.,EX"I$XQD/3R.{{T&ҭ%4[OPnx"HhM :e}-Լ'=s:\iZ<+Lj5+1AɮLZx-☽G3 1I"kuχ+A}5'NxI8 gJk[oenm!x,=n=>}kjPx~M񧍼5k45a,RLiȖTFQMR&K;}r+XkY[y>2F=2~6>Gmi++<[WF76MH4>;;Kf۽ъM3ZE}c㿈*- -.|G5uI![ YR$$A>Eyׇ|7u;n>4׭JϷR[h!rVr\{~Ϛ >0jMg?_y_ Do/x;ÚƏi a𶕦f|Eqgk4V^RY]}F,/J%ՌAud%:x3Hg_4[+^ ҴKaXF'n.]Z(i$bef5GO:u]/a~.3N4xiG*a8ާ-U){G nJEڿ[m7wv5MYp|'gm # #%B?|鿲w­{+_|Q#VkxcZޛ{I]Wyak}..i˨iY9QwOA~hf{+ |Y;cڴ27G>|H,na8o; CEO,ZLP?SHK} e92W7/1aj¤aڄq4 қS7,5]%EƔc/uҒw\r/EnT y>!V+VK4X^Y{;+Ӫ=MqslEn?Zz'Ë}^2xĺGf70/M~*DU=坍G{wwvci%vZ$GY&J9dkՀ\6hs.F*ĩ"+S%s*{ qqDj3$ q^T24,Cn +=j񟍼q5k'\%ݎ{ͦuyq4X$y<ك2Ey%™|Icw]3#R[`{KցY [1*kLOdw ^OAkЏb<¿ <=6x0ׄ>(=*[ t]9-?IZ@}/>FۃQ@ endstream endobj 4 0 obj << /Type /XObject /Subtype /Form /FormType 1 /Filter /FlateDecode /BBox [0.000000 0.000000 595.276000 76.535433] /Matrix [1 0 0 1 0 0] /Resources << /ProcSet [/PDF /Text /ImageB /ImageC /ImageI] /Font << /F2 5 0 R /F1 3 0 R >> /XObject << /I0 18 0 R >> >> /Length 197 >> stream xKkBA WeI&ڊU/ nʥBf8A3!(X4`JQj*Aj͕197f hkL[=µrw]F D%x2WC0 9)Z ^Wh}29yyu?4g=bT1߻a endstream endobj 2 0 obj << /ProcSet [/PDF /Text /ImageB /ImageC /ImageI] /Font << /F1 3 0 R /F2 5 0 R /F3 12 0 R >> /XObject << /XT4 4 0 R /I0 18 0 R >> >> endobj 6 0 obj <> /H /I>> endobj 7 0 obj <> /H /I>> endobj 8 0 obj <> /H /I>> endobj 9 0 obj <> /H /I>> endobj 10 0 obj <> /H /I>> endobj 11 0 obj <> /H /I>> endobj 13 0 obj <> /H /I>> endobj 19 0 obj << /Title (Investigational AKT inhibitor AZD5363 is active against multiple tumor types with AKT1 E17K mutations) /Subject (Investigational AKT inhibitor AZD5363 is active against multiple tumor types with AKT1 E17K mutations) /Creator (Science X Network) /Producer (TCPDF 6.3.5 \(http://www.tcpdf.org\)) /CreationDate (D:20220923045922-04'00') /ModDate (D:20220923045922-04'00') /Trapped /False >> endobj 20 0 obj << /Type /Metadata /Subtype /XML /Length 4859 >> stream application/pdf Investigational AKT inhibitor AZD5363 is active against multiple tumor types with AKT1 E17K mutations Investigational AKT inhibitor AZD5363 is active against multiple tumor types with AKT1 E17K mutations 2022-09-23T04:59:22-04:00 Science X Network 2022-09-23T04:59:22-04:00 2022-09-23T04:59:22-04:00 TCPDF 6.3.5 (http://www.tcpdf.org) uuid:950b7803-752d-5161-a128-f1525f45ac88 uuid:950b7803-752d-5161-a128-f1525f45ac88 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal Adobe PDF Schema InstanceID URI http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text endstream endobj 21 0 obj << /Type /Catalog /Version /1.7 /Pages 1 0 R /Names << >> /ViewerPreferences << /Direction /L2R >> /PageLayout /SinglePage /PageMode /UseNone /OpenAction [14 0 R /FitH null] /Metadata 20 0 R >> endobj xref 0 22 0000000000 65535 f 0000004554 00000 n 0000011090 00000 n 0000004621 00000 n 0000010589 00000 n 0000004727 00000 n 0000011237 00000 n 0000011481 00000 n 0000011721 00000 n 0000011972 00000 n 0000012224 00000 n 0000012466 00000 n 0000004838 00000 n 0000012750 00000 n 0000000015 00000 n 0000000510 00000 n 0000003227 00000 n 0000003705 00000 n 0000004953 00000 n 0000012968 00000 n 0000013644 00000 n 0000018586 00000 n trailer << /Size 22 /Root 21 0 R /Info 19 0 R /ID [ <950b7803752d5161a128f1525f45ac88> <950b7803752d5161a128f1525f45ac88> ] >> startxref 18796 %%EOF