%PDF-1.7 % 14 0 obj << /Type /Page /Parent 1 0 R /LastModified (D:20220827152518-04'00') /Resources 2 0 R /MediaBox [0.000000 0.000000 595.276000 841.890000] /CropBox [0.000000 0.000000 595.276000 841.890000] /BleedBox [0.000000 0.000000 595.276000 841.890000] /TrimBox [0.000000 0.000000 595.276000 841.890000] /ArtBox [0.000000 0.000000 595.276000 841.890000] /Contents 15 0 R /Rotate 0 /Group << /Type /Group /S /Transparency /CS /DeviceRGB >> /Annots [ 7 0 R 8 0 R ] /PZ 1 >> endobj 15 0 obj <> stream x\rF}WLa/UъzMb6[; {. HQ.[N@* Lw=$OϿ*~Wr">?ċ8I3RW/u;y#;< 8!xyRH7yң7 ko ojzIPyB88ŵ1AJY/yC Q큰ՊY7b?NW`q׻I+(Bj@ղwxu"* ȚnK.?KO ^Rpfܶ\r"E{YZaB$E'veR ^(|ܬlO-+m ۑ Z+("4Xyzȋ @3d׋kW2[& .mF ҩ*>% *Վp<¤Hβef 7K"j/I)xK*r`9l`&,if×\ɶ[Z.YJsg/TGRnêLszCe0o=e%`~OJ^@|*^O٠ɡ (+Yx GNxpc Cm;ܖm,O"a2 em Jڱ#F\7dzCU4[ =pk\%KVҾc"0gz̏R`蹐Jj\nx?Oǒc AÑb @嶶A۱R6mϳbXnhû NXb#z޲c z5Spg#đa"0u3X{ Tp7~ܵ#~),PIݛZ5@ `ltWD0:}}c 1v?C? ?l;}lrpLa9 `cr=)?oR"# h~ GX劑lm4}lhO_`jDS (39ae^ YGo.<8DҎUXNnLT}˰ qEfZV"u.x gjĴӇjKX+u:9ꁰ|Ob]/.o&a9%-TlDGNƗV#CJ鐤N(+PRL?GD3H[ϒ}p7% 0F;׵TeG""ߎG#H%n8qdFEx9(t7YњC K,kbeFQ^A[*qI a|>#GC] [ ,ЖQ'E] aŨ!>J`yO1PVP_zOŦ/6Xb}w/ ++4s" ,W6]-*!#R-Фbsѣ tC,-svv~sw|~a '%ɖQ&R2!293 !h7򾦰0 I;|\5S7S EqihgH3;.u)g;ܹQ {ǚP*S0!;2"G%jJ( ;k$i';<(Qa gb] sZCpsTovcb|[J=[5r*Ii(]HқpPf=:x),@SLDغA͞f$NU:?l5@(o q_INu49*l-tqatBq7+oYr6c]9ۡ6h,8eńS:3@GA.6L/Jlϑlc$2gh &t hP8Ye,on*D -VȽ3OD#z@B5ΒV.ڼ XviZPK;D!zJ0.R2y1:8(\ŵ(?'aFڲ|#JlYQ:7<:{c >4yAX^ u=3 gaZhb4TE5|G3#3gIPq?/~j6Vrlwݛ靈9xZ-tE ˿b.Ʌt>g ;v}œ)q$)gI˂w!lk;/ F񟀼 ho endstream endobj 16 0 obj << /Type /Page /Parent 1 0 R /LastModified (D:20220827152518-04'00') /Resources 2 0 R /MediaBox [0.000000 0.000000 595.276000 841.890000] /CropBox [0.000000 0.000000 595.276000 841.890000] /BleedBox [0.000000 0.000000 595.276000 841.890000] /TrimBox [0.000000 0.000000 595.276000 841.890000] /ArtBox [0.000000 0.000000 595.276000 841.890000] /Contents 17 0 R /Rotate 0 /Group << /Type /Group /S /Transparency /CS /DeviceRGB >> /Annots [ 9 0 R 10 0 R 11 0 R 12 0 R 13 0 R ] /PZ 1 >> endobj 17 0 obj <> stream xX[8~ϯ83RcnV+5} $T103[FX;WQ|`>w bsyŴf{l {f/q`p8ƒ(Y]xzjOfW"]F0JoqP3N- ^$mSbs!9uǀ)-pzv.‡a _/.CݧVe֡']''JgITg|]&yql `'vtzwOR4p%$JryNzG6=7Y!ϥD SQKQ]+_τ׾ ^!L.2LI=,,KԊÿE`<"luF\yͤm,lx$@mٲ9̒YaI=껮0 iX?C^"s'³[qV$10I+) ?$2y92˶ >K4 o2@j.ST6Nf LXLdd9 d sao¤Yg3ĭTֽW0(tb]"*9Ge iU`1hRazefLQ@X\VMZo?h2 ,`;%I? endstream endobj 1 0 obj << /Type /Pages /Kids [ 14 0 R 16 0 R ] /Count 2 >> endobj 3 0 obj <> endobj 5 0 obj <> endobj 6 0 obj <> endobj 18 0 obj <> stream JFIFHHExifMM* z(1>?QQ Q HHPaint.NET v3.5.10z%u0`:oCC." }!1AQa"q2#BR$3br %&'()*456789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz w!1AQaq"2B #3Rbr $4%&'()*56789:CDEFGHIJSTUVWXYZcdefghijstuvwxyz ?(f 1T$`9Sw(B@;~(]Cd꾫Es:aݻd2\(2F][&]ۢϲ|W͵L@A A 8 (CĝCglZE/ |Ezє{ xQʒ@[ྊ\/I4R0?6.7`ŴwPu|3/Z@Ogi}cFdFKoj?~8|p_A<ĺOkGPK $wRmkmF;YVx&rLj#p ׭axf|s$Ӿc:Qwm]N)Cψ[eYba98xB+oTÚwcRþ$U[ ?qΙ{&jv6Xo$=ԗ&7zgAxIִ.$3,mwc{+%g[!U@&Fϻm/#hci'7n[%It.&/ֶ+Zl~:wi~D>$}o+}@.[/+B6mnt8bi{zc.~F{eUe86g3 VT&> BK VؘXzSMesoM_&ϔIÍK?+hڿnt_ K]H '̽yrWA=O+|"!gɤItXe>Xs hwwG Eouqa /ş_~~'x} ]_^]/ 蚼:<cu/ h&omEۯicǪ\[,k}_uS}㏆W]G^tmf`Ks ]=va&h9n忔>75NWQτ0of,E (˰8hBC_ Jq'W UQKz,N>+`S%}b5ISJ]+(&QVN>eoy7xG4[]]3K{i$I>g-(mbynLIC,"*3f?-%`lfPx涽X"H'h"ֈ(TfeU:܉,a,R*I4xcxalOhGр|ia$cg,{gAHEu->]F,{-.,EX"I$XQD/3R.{{T&ҭ%4[OPnx"HhM :e}-Լ'=s:\iZ<+Lj5+1AɮLZx-☽G3 1I"kuχ+A}5'NxI8 gJk[oenm!x,=n=>}kjPx~M񧍼5k45a,RLiȖTFQMR&K;}r+XkY[y>2F=2~6>Gmi++<[WF76MH4>;;Kf۽ъM3ZE}c㿈*- -.|G5uI![ YR$$A>Eyׇ|7u;n>4׭JϷR[h!rVr\{~Ϛ >0jMg?_y_ Do/x;ÚƏi a𶕦f|Eqgk4V^RY]}F,/J%ՌAud%:x3Hg_4[+^ ҴKaXF'n.]Z(i$bef5GO:u]/a~.3N4xiG*a8ާ-U){G nJEڿ[m7wv5MYp|'gm # #%B?|鿲w­{+_|Q#VkxcZޛ{I]Wyak}..i˨iY9QwOA~hf{+ |Y;cڴ27G>|H,na8o; CEO,ZLP?SHK} e92W7/1aj¤aڄq4 қS7,5]%EƔc/uҒw\r/EnT y>!V+VK4X^Y{;+Ӫ=MqslEn?Zz'Ë}^2xĺGf70/M~*DU=坍G{wwvci%vZ$GY&J9dkՀ\6hs.F*ĩ"+S%s*{ qqDj3$ q^T24,Cn +=j񟍼q5k'\%ݎ{ͦuyq4X$y<ك2Ey%™|Icw]3#R[`{KցY [1*kLOdw ^OAkЏb<¿ <=6x0ׄ>(=*[ t]9-?IZ@}/>FۃQ@ endstream endobj 4 0 obj << /Type /XObject /Subtype /Form /FormType 1 /Filter /FlateDecode /BBox [0.000000 0.000000 595.276000 76.535433] /Matrix [1 0 0 1 0 0] /Resources << /ProcSet [/PDF /Text /ImageB /ImageC /ImageI] /Font << /F2 5 0 R /F1 3 0 R >> /XObject << /I0 18 0 R >> >> /Length 197 >> stream xKkBA WeI&ڊU/ nʥBf8A3!(X4`JQj*Aj͕197f hkL[=µrw]F D%x2WC0 9)Z ^Wh}29yyu?4g=bT1߻a endstream endobj 2 0 obj << /ProcSet [/PDF /Text /ImageB /ImageC /ImageI] /Font << /F1 3 0 R /F2 5 0 R /F3 6 0 R >> /XObject << /XT4 4 0 R /I0 18 0 R >> >> endobj 7 0 obj <> /H /I>> endobj 8 0 obj <> /H /I>> endobj 9 0 obj <> /H /I>> endobj 10 0 obj <> /H /I>> endobj 11 0 obj <> /H /I>> endobj 12 0 obj <> /H /I>> endobj 13 0 obj <> /H /I>> endobj 19 0 obj << /Title (Novel combination therapy effective for NRAS mutant and therapy resistant melanoma) /Subject (Novel combination therapy effective for NRAS mutant and therapy resistant melanoma) /Creator (Science X Network) /Producer (TCPDF 6.3.5 \(http://www.tcpdf.org\)) /CreationDate (D:20220827152518-04'00') /ModDate (D:20220827152518-04'00') /Trapped /False >> endobj 20 0 obj << /Type /Metadata /Subtype /XML /Length 4821 >> stream application/pdf Novel combination therapy effective for NRAS mutant and therapy resistant melanoma Novel combination therapy effective for NRAS mutant and therapy resistant melanoma 2022-08-27T15:25:18-04:00 Science X Network 2022-08-27T15:25:18-04:00 2022-08-27T15:25:18-04:00 TCPDF 6.3.5 (http://www.tcpdf.org) uuid:305c8a10-d6d4-59e6-caa7-586f7fc49371 uuid:305c8a10-d6d4-59e6-caa7-586f7fc49371 http://ns.adobe.com/pdf/1.3/ pdf Adobe PDF Schema internal Adobe PDF Schema InstanceID URI http://ns.adobe.com/xap/1.0/mm/ xmpMM XMP Media Management Schema internal UUID based identifier for specific incarnation of a document InstanceID URI http://www.aiim.org/pdfa/ns/id/ pdfaid PDF/A ID Schema internal Part of PDF/A standard part Integer internal Amendment of PDF/A standard amd Text internal Conformance level of PDF/A standard conformance Text endstream endobj 21 0 obj << /Type /Catalog /Version /1.7 /Pages 1 0 R /Names << >> /ViewerPreferences << /Direction /L2R >> /PageLayout /SinglePage /PageMode /UseNone /OpenAction [14 0 R /FitH null] /Metadata 20 0 R >> endobj xref 0 22 0000000000 65535 f 0000004886 00000 n 0000011421 00000 n 0000004953 00000 n 0000010920 00000 n 0000005059 00000 n 0000005170 00000 n 0000011567 00000 n 0000011810 00000 n 0000012053 00000 n 0000012319 00000 n 0000012586 00000 n 0000012876 00000 n 0000013165 00000 n 0000000015 00000 n 0000000491 00000 n 0000003272 00000 n 0000003770 00000 n 0000005284 00000 n 0000013383 00000 n 0000013983 00000 n 0000018887 00000 n trailer << /Size 22 /Root 21 0 R /Info 19 0 R /ID [ <305c8a10d6d459e6caa7586f7fc49371> <305c8a10d6d459e6caa7586f7fc49371> ] >> startxref 19097 %%EOF